Since Onefinity uses open loop stepper motors that can move while the machine is off, the big challenge after power off or power loss will be having a reliable zero point to start from that you can then apply your stored offset. This will be influenced by the required level of precision, stall homing in my testing was +/- 0.005" which may be good enough. I’ve moved to homing switches which are in the +/- 0.0002" realm (realistically there seems to be less error but my most accurate dial indicator is limited to 0.0002")
I also use fixtures for many operations where the corner of the fixture is my zero point, after power loss or when making another one of a part I use that as my work offset in CAM and on the Onefinity