No, this is all within the machine coordinates system (MCS). When you zero on your part, you’re doing that in the work coordinate system (WCS). So all cutting is relative to WCS.
Also I’m sure there’s other ways within the Post Processor to adjust these settings, but I was just goofing around, and stumbled across this and figured I’d try it, and it worked 
- as I was getting tired of the unit returning to the front left corner after each process (I prefer a machine to finish away from where I’m standing 